Ophthalmic suspension
To treat glaucoma or ocular hypertension (a glaucoma-like condition).
Glaucoma and ocular hypertension, both sight-threatening disorders, occur when poor drainage of aqueous humor (the fluid inside the front part of the eye) increases the pressure within the eyeball (known as intraocular pressure). Increased intraocular pressure can damage the optic nerve and lead to a gradual loss of vision. By inhibiting the activity of the enzyme carbonic anhydrase, brinzolamide decreases the production of aqueous humor, and reduces intraocular pressure.
Adults and teenagers: 1 drop in affected eye(s) 3 times per day.
Unknown.
Unknown.
No special restrictions.
Store in a tightly sealed container away from heat, moisture, and direct light. Do not refrigerate or allow it to freeze.
Apply it as soon as you remember. If it is near the time for the next dose, skip the missed dose and resume your regular dosage schedule. Do not double the next dose.
The decision to stop using the drug should be made by your doctor.
Schedule regular eye examinations with your doctor to be sure the drug is controlling the glaucoma or ocular hypertension.
No special problems are expected.
Do not drive or engage in hazardous work until you determine how the medicine affects your vision.
No special precautions are necessary.
One animal study found that very high doses of this drug caused birth defects. Human studies have not been done. Before using this medicine, tell your doctor if you are pregnant or plan to become pregnant.
It is not known whether brinzolamide passes into breast milk; caution is advised. Consult your doctor for specific advice about whether to use a different medicine or to stop breast feeding.
Safety and dosage for children have not been established. Brinzolamide should be given to infants and children only under close medical supervision.
To use the eye drops, first wash your hands. Tilt your head back. Gently apply pressure to the inside corner of the eyelid and with the index finger of the same hand, pull downward on the lower eyelid to make a space. Drop the medicine into this space and close your eye. Apply pressure for 1 or 2 minutes while keeping the eye closed without blinking. Then wash your hands again. Make sure that the tip of the dropper does not touch your eye, finger, or any other surface.
No specific ones have been reported.
An overdose of brinzolamide is unlikely to be life-threatening. If a large volume enters the eye, flush with water. If someone accidentally ingests the medicine, call your doctor, emergency medical services (EMS), or the nearest poison control center.
Wait 10 minutes before administering any other eye medicine. Brinzolamide should not be used in conjunction with oral carbonic anhydrase inhibitors. People allergic to sulfa-type drugs should not use brinzolamide.
No known food interactions.
Do not use if you have severe kidney impairment. Use with caution if you have liver disease.