Capsules
To treat rheumatoid arthritis. Because of the risk of highly unpleasant side effects, auranofin is generally prescribed for patients who have not responded adequately to other more conservative arthritis treatments, such as nonsteroidal anti-inflammatory drugs, corticosteroids, and aspirin. (Auranofin is not appropriate for the treatment of osteoarthritis, which is much more common.)
Auranofin contains gold. It is not precisely known how gold compounds work, but evidently they reduce some of the painful joint inflammation associated with arthritis. Auranofin can halt the progress of severe rheumatoid arthritis, preventing further joint damage, and in some cases it may bring about a remission from the disease.
Adults: 6 mg once a day, or 3 mg twice a day. After 6 months of therapy, your doctor may increase the dose to 3 mg, 3 times a day. Children: Consult your pediatrician for proper dosage.
Within 3 to 4 months.
Unknown.
Maintain your usual food and fluid intake.
Store in a tightly sealed container away from heat and direct light.
Take the missed dose as soon as you remember. If you are within 2 hours of your next scheduled dose, skip the missed dose. Take your next scheduled dose at the proper time, then resume your regular dosage schedule. Do not double the next dose.
This medication should be taken as prescribed for the full treatment period. Do not stop taking it on your own if you are feeling better before the scheduled end of drug therapy unless you are experiencing a serious side effect.
Several months of therapy may be necessary to determine whether this medication is helping you. Prolonged use of auranofin may increase the risk of side effects.
Adverse reactions may be more likely and more severe in older patients.
The use of auranofin may impair your ability to perform such tasks safely.
Avoid alcohol while taking this drug.
Do not use this drug during pregnancy.
Auranofin passes into breast milk; avoid or discontinue use while nursing.
Not recommended.
Gold compounds may have many adverse effects resulting from gold toxicity. Your doctor will order periodic blood tests to determine if you are having any undesirable reactions to auranofin, such as anemia or low white blood cell count. Always contact your doctor if you have any concerns about the way you feel while taking auranofin. Auranofin may cause heightened sensitivity to sunlight. Avoid direct sunlight during peak hours, and wear protective clothing. Use sunscreens if possible.
No cases of overdose have been reported.
If you are concerned about the possibility of an overdose, contact your doctor, emergency medical services (EMS), or the nearest poison control center immediately.
Consult your doctor for specific advice if you are taking penicillamine.
No known food interactions.
Consult your doctor if you have anemia or any other blood disease, skin disease, colitis or any other intestinal disease, ulcers or heartburn, kidney disease, or systemic lupus erythematosus (SLE).