Tablets, capsules
To relieve angina (chest pain associated with heart disease) and to treat hypertension.
Amlodipine interferes with the movement of calcium into heart muscle cells and the smooth muscle cells in the walls of the arteries. This action relaxes blood vessels (causing them to widen), which lowers blood pressure, increases the blood supply to the heart, and decreases the heart's overall workload.
2.5 to 10 mg per day in one daily dose (usually in the morning, with breakfast).
One to two hours.
24 hours.
It can be taken with or after meals to minimize stomach irritation. Be sure to follow a low-sodium, low-fat diet if your doctor so advises.
Store in a tightly sealed container away from heat and direct light.
If you miss a dose, take it as soon as you remember, unless the next dose is less than four hours away. In that case, skip the missed dose and go back to your regular schedule. Do not double the next dose.
Take as prescribed for the full treatment period. Do not stop taking this drug suddenly, as this may cause potentially serious health problems. If therapy is to be discontinued, dosage should be reduced gradually, according to doctor's instructions.
In some cases amlodipine therapy may be required for years or even a lifetime. Consult your doctor about the need for medical or laboratory tests of heart activity, blood pressure, kidney function, and liver function.
Adverse reactions may be more likely and more severe in older patients. Smaller doses (2.5 mg per day) are generally prescribed.
Avoid driving or engaging in hazardous work until you determine how this medication affects you. Be cautious if it causes dizziness.
Alcohol should be used with caution because it may increase the effect of the drug and cause an excessive drop in blood pressure.
Amlodipine should not be taken during the first three months of pregnancy and should be used in the last six months only if your doctor so advises.
Amlodipine should not be taken by nursing mothers.
Amlodipine is not usually prescribed for patients under the age of 12.
Amlodipine should not be taken by anyone who has had a prior adverse reaction to it. When taking amlodipine, avoid sudden changes in position, especially standing up quickly after sitting or lying down; such movements may cause dizziness.
Severe drop in blood pressure resulting in weakness, dizziness, drowsiness, confusion, or slurred speech.
Call your doctor, emergency medical services (EMS), or your local hospital immediately.
Other heart drugs taken with amlodipine can cause heart rate and rhythm problems. In general, consult your doctor if you are taking any other prescription or nonprescription drugs.
Avoid excessive intake of foods high in sodium.
Consult your doctor if you have kidney disease, liver disease, high blood pressure, or any heart disease other than coronary artery disease.